Supportive Evidence
Ear canal
More evidence
A new study by Oulu University found large amounts of a light-sensitive OPN4-protein, melanopsin, in the human brain. The mood-enhancing influence and circadian pacemaking properties of bright light when administered through eyes has been shown in earlier studies to be based on the OPN4-protein. In those studies the protein was found only on the retina. This new discovery now confirms that bright light, when channeled through the ear canal into the brain, can have an influence on brain functions.
Timo Ahopelto
 |
Molecular Biology
The study, done at Oulu University, was presented in March at the European Congress of Psychiatry in Prague. The OPN4-protein was originally discovered in 2000 when it was found on the retina. In the more recent study at Oulu University the same protein was found in all the 17 sites of the human brain that were being studied. The presence of the protein was confirmed using methods of molecular biology.
Melanopsin
“The discovery of the research team confirms that some of the brain cells may be photosensitive. OPN4-protein, also known as melanopsin, is present in brain cells that have a central role in modulation of several vital functions, including the circadian rhythm”, says Professor Seppo Saarela of the Oulu University biology department, who led the study. “Often findings of even classical status are worth re-confirming with additional measurements by several research groups, utilizing improved methods. The present study succeeded in locating melanopsin despite the negative results by the earlier studies. Never before have these measurements been completed on as much human samples as was used in the study now reported”, emphasizes Saarela.
Valkee
The new research findings are supportive of effects of bright light therapy administered directly into the brain through the ear canal. “Discovery of the photosensitive OPN4-protein in several parts of the human brain adds to the body of evidence that bright light channeled to the brain directly – not just through the eyes – can modulate brain functions”, says Chief Science Officer Juuso Nissila from Finnish company Valkee Oy. The molecules of the opsin family are extremely sensitive to quantities of light that have been already shown in studies decades ago to penetrate all the way into central parts of the brain”, he emphasizes.
Seasonal Affective Disorder
Bright light is widely recognized as an effective therapy for treating Seasonal Affective Disorder. The Valkee bright light headset is based on research findings on photosensitivity of the brain: light is channeled through the ear canal directly to regions of the brain that are known to be central to depression and that have been discovered to contain photosensitive proteins in studies at the Oulu University. Already earlier, in 2011, a research group in Oulu found a photosensitive OPN3-protein (encephalopsin, panopsin) in the human brain.
Oh my goodness! Impressive article dude! Thank you, However I am going through problems with your RSS. I don’t understand the reason why I cannot join it. Is there anybody else getting similar RSS issues? Anyone that knows the answer will you kindly respond? Thanx!!
Great info. Lucky me I recently found your website by accident (stumbleupon). I have book marked it for later!
After I originally left a comment I seem to have clicked on the -Notify me when new comments are added- checkbox and from now on each time a comment is added I get four emails with the exact same comment. There has to be a way you are able to remove me from that service? Cheers.
bookmarked!!, I like your web site!
After looking over a number of the blog articles on your website, I seriously like your technique of writing a blog. I saved it to my bookmark website list and will be checking back soon. Take a look at my website as well and tell me your opinion.
I blog quite often and I seriously appreciate your information. Your article has truly peaked my interest. I will book mark your website and keep checking for new information about once per week. I opted in for your Feed too.
After I originally commented I seem to have clicked on the -Notify me when new comments are added- checkbox and now whenever a comment is added I receive 4 emails with the same comment. Is there an easy method you can remove me from that service? Many thanks.
Your style is unique compared to other people I have read stuff from. Many thanks for posting when you’ve got the opportunity, Guess I will just book mark this site.
I was able to find good information from your content.
You made some decent points there. I looked on the web for additional information about the issue and found most people will go along with your views on this site.
This is a topic that’s close to my heart… Take care! Exactly where are your contact details though?
Major thankies for the post.Really looking forward to read more. Really Great.
I really like and appreciate your blog.Thanks Again. Great.
Very neat blog.Thanks Again.
I appreciate you sharing this blog.Really thank you! Awesome.
Im thankful for the blog.
Major thankies for the article.Much thanks again. Fantastic.
Hey, thanks for the blog article.
Muchos Gracias for your blog.Much thanks again. Much obliged.
A big thank you for your blog.Much thanks again. Want more.
Thanks-a-mundo for the blog. Really Great.
A round of applause for your article. Cool.
Major thanks for the article.Much thanks again. Will read on…
Muchos Gracias for your article. Really thank you! Fantastic.
I am so grateful for your post. Keep writing.
A big thank you for your blog post. Really looking forward to read more. Really Great.
Thanks a lot for the article post.Much thanks again. Keep writing.
Im thankful for the blog.Really thank you! Great.
Major thanks for the blog article. Really looking forward to read more. Will read on…
Thank you ever so for you article.Really looking forward to read more. Will read on…
A big thank you for your blog post.Really thank you! Great.
I loved your blog.Really thank you! Fantastic.
Im grateful for the blog. Will read on…
Looking forward to reading more. Great blog post. Will read on…
Enjoyed every bit of your blog article. Cool.
I appreciate you sharing this blog post.Thanks Again. Keep writing.
I appreciate you sharing this article post. Really Great.
Appreciate you sharing, great post.Really thank you! Cool.
Major thanks for the post.Really thank you! Really Cool.
I am so grateful for your post.Really thank you! Cool.
Say, you got a nice blog post.Really thank you! Really Cool.
Major thanks for the post.Thanks Again. Much obliged.
Major thanks for the article.Thanks Again. Really Great.
Thanks for the article.Thanks Again. Much obliged.
Very neat blog.Really looking forward to read more. Cool.
Major thanks for the blog.Really looking forward to read more. Great.
A big thank you for your blog article.Really thank you! Will read on…
I appreciate you sharing this blog. Great.
I am so grateful for your blog.Much thanks again. Cool.
I cannot thank you enough for the blog post.Thanks Again. Keep writing.
Enjoyed every bit of your post.Much thanks again. Really Cool.
Appreciate you sharing, great post. Want more.
Thank you for your article.Really looking forward to read more. Will read on…
Hey, thanks for the blog.Much thanks again. Great.
Say, you got a nice article.Really looking forward to read more. Fantastic.
Great, thanks for sharing this blog article.Really looking forward to read more. Fantastic.
I really like and appreciate your post.Really thank you! Much obliged.
Thank you for your blog. Awesome.
I am so grateful for your blog.Really thank you! Great.
Im obliged for the blog post.Thanks Again. Cool.
Thanks a lot for the article.Thanks Again. Keep writing.
Thanks a lot for the article. Will read on…
Major thanks for the blog post. Fantastic.
Muchos Gracias for your article. Awesome.
I think this is a real great post.Really thank you! Much obliged.
Thanks so much for the article post. Awesome.
I appreciate you sharing this blog post.Thanks Again. Much obliged.
Major thankies for the article.Thanks Again. Want more.
I am so grateful for your blog.Really looking forward to read more. Want more.
I really liked your blog.Much thanks again. Want more.
I think this is a real great article post.Really looking forward to read more. Will read on…
Great blog.Really looking forward to read more. Cool.
Appreciate you sharing, great blog post.Thanks Again. Cool.
Very good article.Thanks Again.
Im grateful for the blog article.Really thank you! Keep writing.
Thanks for the article post.Really looking forward to read more. Keep writing.
I value the post.Really looking forward to read more. Awesome.
Major thanks for the blog.Really looking forward to read more. Much obliged.
Major thanks for the blog article. Great.
Say, you got a nice article.Really looking forward to read more. Want more.
Really enjoyed this blog article.Much thanks again. Really Cool.
I truly appreciate this article post.Really looking forward to read more. Will read on…
Im thankful for the article post. Want more.
Very informative post.Really thank you! Really Great.
Say, you got a nice blog article.Thanks Again. Great.
I loved your blog article.Really thank you! Fantastic.
Thanks a lot for the blog post.Thanks Again. Will read on…
Enjoyed every bit of your post.Much thanks again. Keep writing.
Looking forward to reading more. Great article.Really looking forward to read more. Great.
Thanks-a-mundo for the blog article.Thanks Again. Will read on…
Im obliged for the post.Much thanks again. Cool.
Appreciate you sharing, great post.Really thank you! Will read on…
Major thanks for the blog.Much thanks again. Want more.
Hey, thanks for the blog post.Really thank you! Cool.
Hey, thanks for the article post.Much thanks again. Much obliged.
Major thanks for the blog.Thanks Again. Keep writing.
I really like and appreciate your article post.Really thank you! Fantastic.
Major thanks for the article.Really thank you! Much obliged.
Very informative article. Really Great.
I really liked your blog post.Much thanks again. Fantastic.
I loved your article.Thanks Again. Fantastic.
Appreciate you sharing, great blog post.Really thank you! Will read on…
Really appreciate you sharing this blog post.Really looking forward to read more. Keep writing.
I appreciate you sharing this blog.Really looking forward to read more. Want more.
Really informative blog.Thanks Again. Fantastic.
Hey, thanks for the article post.Really thank you! Awesome.
Awesome blog article.Really looking forward to read more. Awesome.
Thanks for the blog post.Much thanks again. Cool.
Looking forward to reading more. Great blog.Really thank you! Great.
Inmiddels blijkt bij onafhankelijk onderzoek dat er geen invloed op melatoninespiegels teweeg gebracht wordt. Dat haalt het verhaal onderuit. Ook blijft er in degelijk dubbelblind onderzoek niet veel meer over van de claims. Vernietigend verhaal: http://ylioppilaslehti.fi/2014/11/let-there-be-valkee-how-a-finnish-startup-managed-to-fool-everyone/